Type: | Package |
Title: | Analyzing the Heterogeneity of Single-Cell Populations |
Version: | 0.2.0 |
Description: | A bioinformatics method developed for analyzing the heterogeneity of single-cell populations. Phitest provides an objective and automatic method to evaluate the performance of clustering and quality of cell clusters. |
License: | GPL-3 |
Encoding: | UTF-8 |
RoxygenNote: | 7.1.1 |
Imports: | parallel, fitdistrplus |
Suggests: | knitr, rmarkdown |
VignetteBuilder: | knitr |
NeedsCompilation: | no |
Packaged: | 2022-01-21 01:33:49 UTC; wei |
Author: | Wei Vivian Li |
Maintainer: | Wei Vivian Li <vivian.li@rutgers.edu> |
Repository: | CRAN |
Date/Publication: | 2022-01-21 09:13:00 UTC |
Appling the Phitest method to a count matrix
Description
Phitest for analyzing the heterogeneity of single-cell populations
Usage
phitest(object, label, ncores = 1, min.cell = 10)
Arguments
object |
A matrix of single-cell UMI counts (rows for genes and columns for cells). |
label |
A character or numeric vector of cluster labels. Length should be the same as
cell number and order should match the order in |
ncores |
Number of cores used for parallel computation. |
min.cell |
An integer specifying a threshold to filter genes. Genes expressed in
fewer than |
Value
A list of two elements: pval
contains the P values, and
par
contains the estimated parameters.
Author(s)
Wei Vivian Li, vivian.li@rutgers.edu